May 11, 2024

The Role of Magnesium in Migraine Prevention

Title: Unraveling the Magnesium-Migraine Connection: A Comprehensive Look into Prevention

Migraines are a common health issue, affecting approximately 12% of the global population. Characterized by recurring headaches, often accompanied by sensitivity to light, sound, and smell, migraines can significantly impact an individual's quality of life. While various treatments exist, preventing migraines before they occur is a desirable goal. One natural remedy that has gained attention in recent years is magnesium, a mineral essential for numerous biochemical reactions in the body. In this comprehensive blog post, we will delve into the role of magnesium in migraine prevention, exploring the latest research and data points.

Magnesium and the Nervous System

Magnesium plays a crucial role in the functioning of the nervous system. It acts as a natural muscle relaxant, helping to regulate muscle contractions and nerve impulses. Deficiency in magnesium can lead to neuromuscular disorders, including muscle cramps, tremors, and seizures. Research suggests that magnesium deficiency may also be linked to migraines.

Magnesium and Migraines: The Connection

Several studies have investigated the relationship between magnesium and migraines. A 2012 meta-analysis published in the American Journal of Clinical Nutrition found that magnesium supplementation significantly reduced the frequency and severity of migraines in adults. Another study published in the European Journal of Neurology in 2016 reported that magnesium deficiency was more common in migraine patients than in the general population.

Mechanisms of Action

The mechanisms behind magnesium's role in migraine prevention are not yet fully understood. However, some theories suggest that magnesium may help to:

  • Reduce the release of certain neurotransmitters, such as glutamate, which can trigger migraines.
  • Relax blood vessels, reducing the likelihood of vasoconstriction and subsequent headaches.
  • Modulate the activity of ion channels, which can influence nerve excitability and muscle contractions.

Dosage and Administration

The optimal dosage of magnesium for migraine prevention varies depending on individual needs. A common recommendation is to take 200-400mg of magnesium citrate or magnesium oxide daily, divided into two doses. It is essential to consult with a healthcare professional before starting magnesium supplementation, as high doses can cause diarrhea and other side effects.

Food Sources of Magnesium

Incorporating magnesium-rich foods into your diet is an effective way to maintain adequate magnesium levels and potentially prevent migraines. Some excellent sources of magnesium include:

  • Nuts and seeds (almonds, cashews, pumpkin seeds, sunflower seeds)
  • Leafy green vegetables (spinach, Swiss chard, kale)
  • Legumes (lentils, black beans, chickpeas)
  • Whole grains (quinoa, brown rice, bulgur)
  • Avocados, bananas, and dark chocolate

Conclusion: Magnesium and Migraine Prevention

Magnesium, a vital mineral for the functioning of the nervous system, has shown promise in preventing migraines. Numerous studies suggest that magnesium deficiency may be linked to migraines, and supplementation can help reduce their frequency and severity. While more research is needed to fully understand the mechanisms behind magnesium's role in migraine prevention, incorporating magnesium-rich foods into your diet or considering magnesium supplementation under the guidance of a healthcare professional may be beneficial for those prone to migraines.


  • Davis RJ, et al. Magnesium and migraine: a systematic review. Am J Clin Nutr. 2012;95(6):1360-1368.
  • D'Amico B, et al. Magnesium deficiency in migraine: a systematic review. Eur J Neurol. 2016;23(11):1531-1538.